Our Biomedical Nanotechnologies team has expertise in 3 research areas:
- synthesis of organic, inorganic, and soft nanostructured materials
- characterization of nanoscale materials
- molecular manipulation of mammalian biology
Current projects include:
- examination of G protein-coupled receptors in inflammation and pseudo-allergic reactions
- nanoencapsulation of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) for targeted delivery
- examination of nanotoxicity
- manipulation of receptor-mediated cellular activation using responsive nanomaterials
- characterization of nanomaterials and biomaterials using cryoEM
- bioegineering of organogel-based materials for drug delivery
Our team oversees several core facilities, including level 1 and level 2 biofacilities, an organic/inorganic chemical synthesis laboratory, and a high-field nuclear magnetic resonance (NMR) facility.
Theory and modelling
Our Theory and Modelling team consists of scientists with diverse expertise in computational nano and biotechnologies. The scope of the team's computational chemistry techniques ranges from ab initio electronic structure methods through classical molecular simulation to mesoscale and continuum simulations. Our team has developed a unique multiscale modelling and simulation approach that serves to obtain novel understanding of the behaviour of biomaterials.
Additional capabilities include:
- chemical reactions in complex environments, nanoengineered materials and systems
- photovoltaics and molecular electronics
- biomolecular conformational change
- self-assembly in complex environments, soft matter, the development of advanced computational methods and machine learning.