•demonstrated that ZV can cross the blood-brain barrier
•showed that ZV infects glioblastoma cells to varying degrees, suggesting that genetically modified ZV could be developed to target therapeutics to glioblastoma cells
•developed a robust mouse model of ZV infection to test potential Zika vaccines
The NRC further leveraged its business relationship with Variation Biotechnologies Inc. (VBI) to bring the company's proprietary vaccine platform into this global effort to fight the emerging Zika epidemic. To this end, VBI and the NRC submitted a joint ZV grant proposal to the National Institute of Health. This strategic collaboration between VBI and the NRC has already led to the development of a plaque reduction neutralization assay at the NRC, and a collaborative research agreement to evaluate VBI's candidate enveloped virus-like particle (eVLP) vaccines is underway.
Research Centre: Advanced Electronics and Photonics
The National Research Council of Canada (NRC) signed a strategic agreement with Brilliant Matters to license the intellectual property of one of their semiconductors. Through this licensing agreement, Brilliant Matters will have access to a high-performing material developed at the NRC. The use of this material will help Brilliant Matters generate higher-performing semiconductors to produce organic photovoltaics at a lower cost. The final product, which will be produced in Canada, will increase the country's competitiveness on the organic semiconductor market and ultimately provide better and more affordable photovoltaics worldwide.
October 20 is World Statistics Day. At the NRC, we use statistics and data on a daily basis, in all of our research areas, to answer questions for our clients and collaborators and to advance scientific knowledge. The NRC’s Digital Technologies Research Centre is particularly active in the analysis of data, and offers a specialized facility called the Data Analytics Centre where government, academic and industrial clients can collaborate with NRC experts to analyze their data.
Research Centre: Industrial Research Assistance Program
Canada and Germany have long-lasting cooperation in science and research and, in December 2017, signed a Joint Declaration of Intent to recognize the existing partnerships between both countries and commit to more collaborations on research and development (R&D), and technological innovation initiatives. As part of this commitment, the Natural Sciences and Engineering Research Council of Canada (NSERC), the National Research Council of Canada Industrial Research Assistance Program (NRC IRAP), and the German Federal Ministry of Education and Research (BMBF) initiated a unique partnership and, in January 2018, launched a successful joint call for proposals on Industry 4.0 and Advanced Manufacturing.
Research Centre: Aquatic and Crop Resource Development
Industry: Agronomics, Crop Development, Nutrition and Nutritional Properties, Human Nutrition
After 13 years of collaborative research involving more than 200 scientists across 73 research institutions in 20 countries, the International Wheat Genome Sequencing Consortium (IWGSC) has finally deciphered the wheat genome code. The detailed description of the genome of bread wheat, the world's most widely cultivated crop, was announced on August 16, 2018 in the international journal Science. The NRC's Raju Datla, Daoquan Xiang, Janet Condie and Yifang Tan contributed to this important research coordinated by IWGSC, which will pave the way for the production of wheat varieties better adapted to climate challenges, with higher yields, enhanced nutritional quality and improved sustainability.