Recognizing that we can accomplish much more by working with others than on our own, the NRC embarked on a bold initiative in 2018‑19: to create collaboration centres with leading Canadian organizations in order to accelerate science excellence and technology development. All of these centres will have a "dedicated" physical location at the NRC, or on partner property, where researchers from both organizations will share access to specialized equipment, work side by side on collaborative projects, and provide training opportunities for young scientists.
A key goal of the National Research Council of Canada's (NRC) Aerospace Research Centre is to advance scientific knowledge in order to stimulate innovation, enhance our capabilities and sustain our relevance as a knowledge generator. Not only do we share our knowledge outwardly with industry and academia, but we also do this inwardly – by providing the opportunity to grow and learn from each other by exchanging ideas among colleagues. One successful example of our approach is the Early Career Network (ECN), a collective of early career employees, visiting workers and students from the NRC's Aerospace Research Centre.
In keeping with the Government of Canada's "cloud-first" digital principle, the NRC opted to implement a cloud-based solution, hosted and maintained in a highly secure, Canadian data centre. The NRC also chose to adopt a commercially available solution rather than go the traditional "built for government" path - SuccessFactors provides best-in-class standardized business processes with data integration across modules leveraging a consumer-grade web interface.
The hallmark of the National Research Council's (NRC)Design and Fabrication Services Branch is its ability to work with NRC researchers in a responsive, collaborative manner, leveraging the diverse capabilities of the branch in direct support of important research and technical services. This is the case even if the work must move from one part of the country to another to stay at the pace of innovation. With 13 shops spread across Canada, Design and Fabrication Services delivers design and fabrication services that meet demanding requirements for apparatus, fixturing, experiment setups and technical services for the NRC's contributions to academia, industry and major international partnerships.
•demonstrated that ZV can cross the blood-brain barrier
•showed that ZV infects glioblastoma cells to varying degrees, suggesting that genetically modified ZV could be developed to target therapeutics to glioblastoma cells
•developed a robust mouse model of ZV infection to test potential Zika vaccines
The NRC further leveraged its business relationship with Variation Biotechnologies Inc. (VBI) to bring the company's proprietary vaccine platform into this global effort to fight the emerging Zika epidemic. To this end, VBI and the NRC submitted a joint ZV grant proposal to the National Institute of Health. This strategic collaboration between VBI and the NRC has already led to the development of a plaque reduction neutralization assay at the NRC, and a collaborative research agreement to evaluate VBI's candidate enveloped virus-like particle (eVLP) vaccines is underway.