Janelle Sauvageau

 

Roles and responsibilities

Janelle Sauvageau works as a Research Officer in the glyco-chemistry team in HHT. She synthesises and analyze charged glycans and develop syntheses for vaccines and immunomodulators. Her main project is the synthesis of phosphated heptoses as immunomodulators. She is the chair of the chemical safety committee where their safe disposal and inventory is the main goal of the committee.

Current research and/or projects

Janelle Sauvageau is an expert in carbohydrate synthesis and analysis. Her contribution is to apply this field to human health therapeutics.

Research and/or project statements

-Synthesis of charged carbohydrate to access their potential as immunomodulators

-Analysis of carbohydrates using ion exchange and electrochemical detection

-Synthesis of glycans for assessment as conjugate vaccines

-Chairing the chemical committee

Education

Ph.D. Chemistry, Victoria University of Wellington (New Zealand) 2013

M.Sc. Chemistry, Université Laval, 2004

B.Sc. Chemistry, Université Laval, 2004

Professional activities/interests

Work with students, organize talks

Affiliations

Adjunct Professor, INRS, Armand-Frappier

Awards

Instant Award, Certificate of Excellence (Ambassador, NRC)

Key publications

Adekoya, I. A., Guo, C. X., Gray-Owen, S. D., D. Cox, A., Sauvageau, J. (2018) d-Glycero-β-d-manno-heptose 1-phosphate and d-glycero-β-d-manno-heptose 1,7-biphosphate are both innate immune agonists. J. Immunol., 201, 2385-2391.

Sauvageau, J., Bhasin, M., Guo, C.X., Gray-Owen, S.D., Oscarson, S., Guazzelli, L., Cox, A. (2017) Alternate synthesis to d-glycero-β-d-manno-heptose 1,7-biphosphate. Carbohydr. Res., 450, 38-43.

Yimei, J., McCluskie, M.J., Zhang, D., Monette, R., Iqbal, U., Moreno, M., Deschatelets, L., Sauvageau, J., Williams, D., Jakubek, Z.J., Krishnan, L. (2017) In vitro evaluation of archaeosome vehicles for transdermal vaccine delivery. ‎J. Liposome Res., 25, 305-314.

Timmer, M., Sauvageau, J., Foster, A. J., Ryan, J., Lagutin, K., Shaw, O., Harper, J. L., Sims I. M., Stocker, B. L. (2014) Discovery of lipids from B. longum subsp. infantis using whole cell MALDI analysis, J. Org. Chem., 79, 7332-7341.

Sauvageau, J., Khan, A., Sims, I., Stocker, B., Timmer, M. (2012) Synthesis and biological activity of the lipotechoic acid anchor from Streptococcus sp. DSM 8747. ChemBioChem, 13, 2416-2424.

Sauvageau, J., Ryan, J., Lagutin, K., Sims, I., Stocker, B., Timmer, M. (2012) Isolation and structural characterisation of the major glycolipids from Lactobacillus plantarum. Carbohydr. Res., 357, 151-156.

Sauvageau, J., Sims, I.M., Hinkley, S. F., Carnachan, S. (2010). Characterisation of polysaccharides from ZESPRI GOLD kiwifruit. Carbohydr. Polym. 82, 1110–1115.

Previous work experience

September 2014— September 2018

NRC

Research Associate

  • Synthesis and synthesis design for different carbohydrate targets
  • Intellectual property protection of discoveries
  • Publish research results

International experience and/or work

April, 2008 — October, 2009

Industrial Research Limited, Wellington, New Zealand

Research Scientist

  • Analysis of biomaterials using GC-MS, NMR and HPLC
  • Synthesis of carbohydrate derivatives
Janelle Sauvageau

Janelle Sauvageau

Associate Research Officer
Human Health Therapeutics
100 Sussex Drive
Ottawa, Ontario K1A 0R6
Preferred language: French
Other(s): German, English, French
Telephone: 613-990-0821

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Expertise

Health, Chemistry, Analytical Chemistry, Vaccine