Certified reference materials

The National Research Council of Canada's (NRC) Metrology Research Centre prepares high-quality and reliable certified reference materials (CRMs) for industrial and academic research.

Our multidisciplinary expertise enables us to offer a comprehensive range of CRMs for comparative analysis. CRMs are invaluable tools for analytical method development, validation, and instrument calibration.

CRMs are available in these major analyte categories:

  • algal and cyanobacterial toxins
  • amino acids
  • contaminants
  • dietary supplements
  • ethanol
  • mycotoxins
  • particle size
  • peptides
  • proteins
  • stable isotopes
  • total element content
  • trace element species
  • veterinary drugs

Our selection of CRMs are applied in the following areas:

  • cannabis and hemp
  • clinical
  • COVID-19
  • environment
  • food safety
  • forensics
  • high purity materials
  • isotope ratio
  • nanomaterials
  • nuclear forensics
  • nutrition

We also have the capacity to develop and produce custom CRM materials based on customer needs. In particular, the production of radioactive CRMs is performed as an on demand service. Please contact us for more information.

The Metrology CRMs are produced in a laboratory compliant with ISO/IEC 17025 and ISO 17034, with approval through the Inter-American Metrology System.

View and order available certified reference materials

The available CRMs can be viewed or ordered on the list of certified reference materials page.

Service standards

Processing and handling time

Our processing times may be longer due to COVID-19 safety protocols. Once an order and all required information is received from the purchaser, the order will be scheduled for shipping on the next available shipping date.

Product availability is included in the list of certified reference materials.


Prices are in Canadian dollars and subject to change without notice. Prices and concentrations for replacement products may be different from previous versions.


As a federal government agency, we are committed to delivering quality services in a cost-effective manner.